Afuco™ Anti-LTA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-071) (CAT#: AFC-TAB-071)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to TNF beta. It is an immunomodulator. It binds to lymphotoxin alpha.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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SEC-HPLC
Figure 1 Afuco™ Anti-LTA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-071) in HPLC
The purity of AFC-TAB-071 was greater than 95% as determined by SEC-HPLC.
Lectin WB
Figure 2 Afuco™ Anti-LTA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-071) in Lectin WB
Western blot analysis of AFC-TAB-071 was performed and fucose was detected by AOL-Biotin and SA-HRP. The result was negative, which indicates that there is no fucose produced.
Lane 1: Reducing AFC-TAB-071 (2 μg)
Lane 2: Reducing mouse anti-human IgG (2 μg)
Lectin ELISA
Figure 3 Afuco™ Anti-LTA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-071) in Lectin ELISA
Lectin ELISA analysis of AFC-TAB-071 was conducted and fucose was detected using AOL-Biotin and SA-HRP
The result indicates that there is almost no fucose produced.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- Neut, ELISA, IF, IP, FuncS, FC
- Conjugate
- Unconjugated
- Generic Name
- Pateclizumab
- Related Disease
- Rheumatoid arthritis (RA)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- LTA; lymphotoxin alpha (TNF superfamily, member 1); TNFB; lymphotoxin-alpha; LT; TNFSF1; LT-alpha; TNF-beta; tumor necrosis factor beta; tumor necrosis factor ligand superfamily member 1;
- Gene ID
- 4049
- UniProt ID
- P01374
Related Resources
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-2017-sdAb | Recombinant Anti-LTA VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
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To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# AFC-TAB-071, RRID: AB_3111283)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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